Article
CD73 polymorphisms are associated with schizophrenia.
Purinergic signalling - 1 Aug 2025
Peng He-Xia, Zhang Li-Li, Jiang Dan, Jian Na, Zhang Ting-Mei, Luo Jia-Guo, Yin Hai-Yan
Abstract excerpt
Ecto-5'-nucleotidase/CD73 enzyme plays a key role in the regulation of extracellular adenosine levels, thereby exerting influence on adenosine homeostasis. Emerging evidence suggests that perturbations in purines and ecto-5'-nucleotidase activity are associated with an augmented susceptibility to schizophrenia. However, the precise impact of genetic variations in CD73 on individuals with schizophrenia remains...
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