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Article

Functional Variants of miR-143 Are Associated with Schizophrenia Susceptibility: A Preliminary Population-Based Study and Bioinformatics Analysis.

Biochemical genetics - 1 Jun 2022

Sargazi Saman, Mirani Sargazi Fariba, Heidari Nia Milad, Sheervalilou Roghayeh, Saravani Ramin, Mirinejad Shekoufeh, Shakiba Mansoor

Abstract excerpt

Single nucleotide polymorphisms within genes encoding microRNAs may alter the expression of microRNAs and their target genes, contributing to the etiology of psychiatric disorders. We aimed to investigate the link between rs4705342T/C and rs4705343T/C polymorphisms in the promoter region of miR-143 and the risk of schizophrenia (SCZ) in a sample of an Iranian population. In this experimental study, a total of 398...

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PMID: 34515927
DOI: 10.1007/s10528-021-10133-z

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