Article
Genetic association of TIE2 with diabetic retinopathy and diabetic macular edema.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) - 1 Jan 2000
Yu Jun, Brelen Marten E, Chan Carmen K M, Chen Zhen Ji, Mohamed Shaheeda, Yam Jason C, Lam Dennis S C, Pang Chi Pui, Tham Clement C, Chen Li Jia
Abstract excerpt
PURPOSE: To evaluate the associations of the TIE2 gene with diabetic retinopathy (DR) and diabetic macular edema (DME). METHODS: This study included a Chinese cohort of 285 non-proliferative DR patients and 433 healthy controls. The DR patients were classified further into those with or without DME. Thirty haplotype-tagging single-nucleotide polymorphisms (SNPs) in TIE2 were genotyped using TaqMan technology....
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