Article
Polymorphisms in TIE2 and ANGPT-1 genes are associated with protection against diabetic retinopathy in a Brazilian population.
Archives of endocrinology and metabolism - 25 May 2023
Dieter Cristine, Lemos Natália Emerim, de Faria Corrêa Nathalia Rodrigues, Assmann Taís Silveira, Pellenz Felipe Mateus, Canani Luís Henrique, de Almeida Brondani Letícia, Bauer Andrea Carla, Crispim Daisy
Abstract excerpt
Objective: The objective of this study was to investigate the association between SNPs in the TIE2 and ANGPT-1 genes and diabetic retinopathy (DR). Subjects and methods: This study comprised 603 patients with type 2 diabetes mellitus (T2DM) and DR (cases) and 388 patients with T2DM for more than 10 years and without DR (controls). The TIE2 rs639225 (A/G) and rs638203 (A/G) SNPs and the ANGPT-1 rs4324901 (G/T) and...
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