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Article

Association of TIMP2 Gene Variants With Development of Diabetic Retinopathy.

In vivo (Athens, Greece) - 1 Jan 2026

Huang Chin-Te, Chien Hsiang-Wen, Wang Kai, Su Shih-Chi, Ting Chin-Han, Yang Shun-Fa, Liao Miao-Yu

Abstract excerpt

BACKGROUND/AIM: Diabetic retinopathy (DR) is a common comorbidity of diabetes involving the formation of abnormal vascular structures in the retina. Tissue inhibitor of metalloproteinases 2 (TIMP2), initially identified as a key mediator of extracellular matrix turnover, is pivotal for inflammatory processes and tissue homeostasis. The current study examined the influence of TIMP2 gene variations on the risk for...

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Identifiers

PMID: 42049446
DOI: 10.21873/invivo.14287
PMCID: PMC13133749

Genes

TIMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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