Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of TIE2 as a susceptibility gene for neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

The British journal of ophthalmology - 1 Jul 2021

Chen Zhen Ji, Ma Li, Brelen Marten E, Chen Haoyu, Tsujikawa Motokazu, Lai Timothy Y, Ho Mary, Sayanagi Kaori, Hara Chikako, Hashida Noriyasu, Tam Pancy Os, Young Alvin L, Nishida Kohji, Tham Clement C, Pang Chi Pui, Chen Li Jia

Abstract excerpt

PURPOSE: The endothelial and cell-specific angiopoietin-Tie pathway plays an important regulatory role in angiogenesis. In this study, we investigated the associations of the TIE2 (tyrosine kinase, endothelial, TEK) gene with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV), using haplotype-tagging single-nucleotide polymorphisms (SNPs) analysis. METHODS: This study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroid
Share to Choroidal Neovascularization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescein Angiography

Share to Genotyping Techniques

Share to Polyps

Share to Receptor, TIE-2

Share to Visual Acuity

Share to Wet Macular Degeneration

Source

Identifiers

PMID: 32152144
DOI: 10.1136/bjophthalmol-2019-315746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of TIE2 as a susceptibility gene for neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.PMID 32152144Read ↗

Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations.Semantic proximity Read ↗

Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population.Semantic proximity Read ↗

ENOS polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in a Chinese Han population.Semantic proximity Read ↗

Genetic association of TIE2 with diabetic retinopathy and diabetic macular edema.Semantic proximity Read ↗

Association of ABCG1 With Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Chinese and Japanese.Semantic proximity Read ↗

COL1A2 polymorphic markers confer an increased risk of neovascular age-related macular degeneration in a Han Chinese population.Semantic proximity Read ↗

Associations of 6p21.3 Region with Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy.Semantic proximity Read ↗

Association of IGFN1 variant with polypoidal choroidal vasculopathy.Semantic proximity Read ↗

Association of Genetic Variants with Polypoidal Choroidal Vasculopathy: A Systematic Review and Updated Meta-analysis.Semantic proximity Read ↗

Association of elastin gene polymorphism to age-related macular degeneration and polypoidal choroidal vasculopathy.Semantic proximity Read ↗

Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians.Semantic proximity Read ↗

Vascular endothelial growth factor gene polymorphisms and risk of neovascular age-related macular degeneration in a Chinese cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.