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Chromosome 15q21-22-related polymorphisms and haplotypes are associated with susceptibility to type-2 diabetic nonproliferative retinopathy.

Genetic testing and molecular biomarkers - 1 May 2012

Hsieh Yao-Yuan, Huang Yu-Chuen, Chang Chi-Chen, Wang Yu-Kuo, Lin Wen-Hsin, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVE: Diabetic retinopathy (DR) is a microvascular complication of diabetes with a complex multifactorial pathogenesis. We aimed to investigate whether chromosome 15q21-22-related gene polymorphisms could be used as markers of DR susceptibility in type 2 diabetic (T2D) individuals. METHODS: Individuals were divided into three groups: (1) T2D with nonproliferative DR (NPDR; n=102); (2) T2D with proliferative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22409602
DOI: 10.1089/gtmb.2011.0092

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