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Article

Genetic variations in anti-diabetic drug targets and COPD risk: evidence from mendelian randomization.

BMC pulmonary medicine - 15 May 2024

Su Yue, Zhang Youqian, Xu Jinfu

Abstract excerpt

BACKGROUND: Previous research has emphasized the potential benefits of anti-diabetic medications in inhibiting the exacerbation of Chronic Obstructive Pulmonary Disease (COPD), yet the role of anti-diabetic drugs on COPD risk remains uncertain. METHODS: This study employed a Mendelian randomization (MR) approach to evaluate the causal association of genetic variations related to six classes of anti-diabetic drug...

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Topics

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Share to Diabetes Mellitus, Type 2
Share to Genetic Variation
Share to Glycated Hemoglobin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoglycemic Agents

Share to Mendelian Randomization Analysis

Share to Potassium Channels, Inwardly Rectifying

Share to Pulmonary Disease, Chronic Obstructive

Share to Risk Factors

Source

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Identifiers

PMID: 38750544
DOI: 10.1186/s12890-024-02959-1
PMCID: PMC11094874

Genes

DPP4
KCNJ11
PPARG
SLC5A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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