Article
Potential Causal Relationship Between Chronic Obstructive Pulmonary Disease and Diabetes: A Bidirectional Two-Sample Mendelian Randomization Study.
International journal of chronic obstructive pulmonary disease - 1 Jan 2025
Wang Xinyan, Chen Xin, Feng Ruizhi, Jiang Hongli, Liu Wei
Abstract excerpt
Purpose: Diabetes, particularly type 2 diabetes (T2D), is a common comorbidity that occurs at a higher frequency in chronic obstructive pulmonary disease (COPD) patients compared to the general population. The COPD-diabetes association is documented epidemiologically and experimentally. Potential mechanisms, including systemic inflammation and metabolic dysregulation, are discussed as plausible pathways. However,...
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