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Article

High-resolution HLA genotyping improves PIRCHE-II assessment of molecular mismatching in kidney transplantation.

Human immunology - 1 May 2024

Crane Clarkson, Niemann Matthias, Dale Bethany, Gragert Loren, Shah Mita, Ingulli Elizabeth, Morris Gerald P

Abstract excerpt

HLA matching in solid organ transplant is performed with the aim of assessing immunologic compatibility in order to avoid hyperacute rejection and assess the risk of future rejection events. Molecular mismatch algorithms are intended to improve granularity in histocompatibility assessment and risk stratification. PIRCHE-II uses HLA genotyping to predict indirectly presented mismatched donor HLA peptides, though...

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Identifiers

PMID: 38749805
DOI: 10.1016/j.humimm.2024.110813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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