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Article

Sex and APOE genotype influence respiratory function under hypoxic and hypoxic-hypercapnic conditions.

Journal of neurophysiology - 1 Jul 2024

Taylor Chase E, Mendenhall Laura E, Sunshine Michael D, Wilson Jessica N, Calulot Chris M, Sun Ramon C, Johnson Lance A, Alilain Warren J

Abstract excerpt

The apolipoprotein E (APOE) gene has been studied due to its influence on Alzheimer's disease (AD) development and work in an APOE mouse model recently demonstrated impaired respiratory motor plasticity following spinal cord injury (SCI). Individuals with AD often copresent with obstructive sleep apnea (OSA) characterized by cessations in breathing during sleep. Despite the prominence of APOE genotype and sex as...

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Identifiers

PMID: 38748407
DOI: 10.1152/jn.00255.2023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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