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Article

Association between PTGS1 polymorphisms and functional outcomes in Chinese patients with stroke during aspirin therapy: Interaction with smoking.

Journal of the neurological sciences - 15 May 2017

Cai Huan, Cai Biyang, Sun Lingli, Zhang Hao, Zhou Shuyu, Cao Liping, Guo Hongquan, Sun Wen, Yan Bernard, Davis Stephen M, Zhang Zhizhong, Liu Xinfeng

Abstract excerpt

PURPOSE: Prostaglandin-Endoperoxide Synthase 1 (PTGS1) and smoking may play important roles in aspirin nonresponsiveness, but the effect of their interaction on stroke outcomes remains largely unknown. We examined the effects of PTGS1 polymorphisms, smoking status, and their interaction on functional outcomes in a cohort of Chinese Han patients with stroke during aspirin therapy. METHODS: A total of 617 ischemic...

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Source

Identifiers

PMID: 28431615
DOI: 10.1016/j.jns.2017.03.014

Genes

PTGS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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