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Molecular genomic and epigenomic characteristics related to aspirin and clopidogrel resistance

20 Jun 2024

Abstract excerpt

Abstract Background Mediators, genomic and epigenomic characteristics involving in metabolism of arachidonic acid by cyclooxygenase (COX) and lipoxygenase (ALOX) and hepatic activation of clopidogrel have been individually suggested as factors associated with resistance against aspirin and clopidogrel. The present multi-center prospective cohort study evaluated whether the mediators, genomic and epigenomic...

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Share to Antiplatelet Therapy and Cardiovascular Diseases
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PMID: 38902747
DOI: 10.1186/s12920-024-01936-1

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