Article
Iron, hemochromatosis genotypes, and risk of infections: a cohort study of 142 188 general population individuals.
Blood - 15 Aug 2024
Mottelson Mathis, Glenthøj Andreas, Nordestgaard Børge Grønne, Ellervik Christina, Petersen Jesper, Bojesen Stig Egil, Helby Jens
Abstract excerpt
ABSTRACT: It is unclear whether risk of infection is increased in individuals with hereditary hemochromatosis and in individuals with low or high plasma iron, transferrin saturation, or ferritin. Therefore, we tested whether high and low iron, transferrin saturation, and ferritin are associated with risk of infections observationally and genetically through HFE genotypes. We studied 142 188 Danish general...
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