Article
Mutation Profile in BCR-ABL1-Negative Myeloproliferative Neoplasms: A Single-Center Experience From India.
Hematology/oncology and stem cell therapy - 1 Jun 2022
Maddali Madhavi, Kulkarni Uday Prakash, Ravindra Niveditha, Arunachalam Arun Kumar, Venkatraman Arvind, Lionel Sharon, Manipadam Marie Therese, Devasia Anup J, Korula Anu, Fouzia N A, Abraham Aby, Srivastava Alok, George Biju, Balasubramanian Poonkuzhali, Mathews Vikram
Abstract excerpt
OBJECTIVE/BACKGROUND: Recurrent somatic mutations in the JAK2, calreticulin (CALR), and the MPL genes are described as drivers of BCR-ABL1-negative myeloproliferative neoplasms (MPN) that includes polycythemia vera (PV), essential thrombocytosis (ET), primary myelofibrosis (PMF), and MPN unclassified (MPN-U). METHODS: We describe the mutation profile and clinical features of MPN cases diagnosed at a tertiary care...
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