Article
Molecular genetics of BCR-ABL1 negative myeloproliferative neoplasms in India.
Indian journal of pathology & microbiology - 1 Jan 2000
Rabade Nikhil, Subramanian P G, Kodgule Rohan, Raval Goutham, Joshi Swapnali, Chaudhary Shruti, Mascarenhas Russel, Tembhare Prashant, Gujral Sumeet, Patkar Nikhil
Abstract excerpt
INTRODUCTION: Over the past decade, we have moved on from a predominantly morphological and clinical classification of myeloproliferative neoplasms (MPN) to a more evolved classification that accounts for the molecular heterogeneity that is unique to this subgroup of hematological malignancies. This usually incorporates mutations in Janus kinase 2 (JAK2), MPL, and calreticulin (CALR) genes. In this manuscript, we...
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