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Article

Molecular Profile of BCR-ABL1 Negative Myeloproliferative Neoplasm in a Moroccan Population.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2024

Soro Somda Georgina Charlène, Amalou Ghita, Benchikh Sara, El Hamouchi Adil, Charoute Hicham, Oukheda Mourad, Abdelouaheb Benani Bennani, Saile Rachid, Lebrazi Halima, Nassereddine Sanaa

Abstract excerpt

INTRODUCTION: Myeloproliferative neoplasms (MPN) are associated with clonal hematopoiesis, genomic instability, hemostasis dysregulation, and immune response. Classic BCR-ABL1 negative myeloproliferative neoplasms (BCR-ABL1 negative MPN), including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF), are frequently associated with somatic abnormalities in JAK2, CALR, and MPL....

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PMID: 39611926
DOI: 10.31557/APJCP.2024.25.11.4013

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