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Article

Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization.

Cardiovascular diabetology - 7 May 2024

Qiu Shi, Liu Zhen, Jiang Wei-Dong, Sun Jin-Hui, Liu Zeng-Qiang, Sun Xiao-Di, Wang Chun-Ting, Liu Wen

Abstract excerpt

BACKGROUND: In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements in cardiovascular disease. However, whether the protective effect of diabetes on aortic dissection is mediated by 3-hydroxybutyrate is unclear. We aimed to investigate the causal effects of...

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Source

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Identifiers

PMID: 38715052
DOI: 10.1186/s12933-024-02266-3
PMCID: PMC11077732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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