Article
Genetic association of inflammatory marker GlycA with lung function and respiratory diseases.
Nature communications - 4 May 2024
Guo Yanjun, Liu Quanhong, Zheng Zhilin, Qing Mengxia, Yao Tianci, Wang Bin, Zhou Min, Wang Dongming, Ke Qinmei, Ma Jixuan, Shan Zhilei, Chen Weihong
Abstract excerpt
Association of circulating glycoprotein acetyls (GlycA), a systemic inflammation biomarker, with lung function and respiratory diseases remain to be investigated. We examined the genetic correlation, shared genetics, and potential causality of GlycA (N = 115,078) with lung function and respiratory diseases (N = 497,000). GlycA showed significant genetic correlation with FEV1 (rg = -0.14), FVC (rg = -0.18), asthma...
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