Article
The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan.
The Journal of clinical endocrinology and metabolism - 1 Mar 2006
Ikegami Hiroshi, Awata Takuya, Kawasaki Eiji, Kobayashi Tetsuro, Maruyama Taro, Nakanishi Koji, Shimada Akira, Amemiya Shin, Kawabata Yumiko, Kurihara Susumu, Tanaka Shoichiro, Kanazawa Yasuhiko, Mochizuki Mie, Ogihara Toshio
Abstract excerpt
CONTEXT: Transracial studies are a powerful tool for genetic association studies of multifactorial diseases, such as type 1 diabetes. The low incidence of type 1 diabetes in Asian countries, however, makes it difficult to perform large-scale studies in Asia. OBJECTIVE: To overcome this, we have assembled a multicenter study group in Japan and studied the association of CTLA4 polymorphisms with type 1 diabetes...
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