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Article

HLA Class I Association With Autoimmune Diabetes in Chinese People: Distinct Implications in Classic Type 1 Diabetes and LADA.

The Journal of clinical endocrinology and metabolism - 16 Jun 2023

Xia Ying, Chen Yan, Li Xia, Luo Shuoming, Lin Jian, Huang Gan, Xiao Yang, Chen Zhiying, Xie Zhiguo, Zhou Zhiguang

Abstract excerpt

CONTEXT: We aimed to investigate whether human leukocyte antigen (HLA) Class I loci differentially modulated the risk for and clinical features of Chinese people with classic type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA). METHODS: In this case-control study, genotypes of HLA-A, -B, -C, -DRB1, -DQA1, and -DQB1 loci were obtained from 1067 cases with classic T1D, 1062 cases with LADA, and...

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PMID: 36652403
DOI: 10.1210/clinem/dgad006

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