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The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport

1 May 2024

Abstract excerpt

Abstract Single nucelotide polymorphisms (SNPs) at the FAM13A locus are among the most commonly reported risk alleles associated with chronic obstructive pulmonary disease (COPD) and other respiratory diseases; however, the physiological role of FAM13A is unclear. In humans, two major protein isoforms are expressed at the FAM13A locus: “long” and “short,” but their functions remain unknown, partly because of a...

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PMID: 38691660
DOI: 10.1165/rcmb.2024-0063oc

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