Article
Motile cilia and airway disease.
Seminars in cell & developmental biology - 1 Feb 2021
Legendre Marie, Zaragosi Laure-Emmanuelle, Mitchison Hannah M
Abstract excerpt
A finely regulated system of airway epithelial development governs the differentiation of motile ciliated cells of the human respiratory tract, conferring the body's mucociliary clearance defence system. Human cilia dysfunction can arise through genetic mutations and this is a cause of debilitating disease morbidities that confer a greatly reduced quality of life. The inherited human motile ciliopathy disorder,...
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