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Article

Temperature-sensitive mutants of RNase E in Salmonella enterica.

Journal of bacteriology - 1 Dec 2011

Hammarlöf Disa L, Liljas Lars, Hughes Diarmaid

Abstract excerpt

RNase E has an important role in mRNA turnover and stable RNA processing, although the reason for its essentiality is unknown. We isolated conditional mutants of RNase E to provide genetic tools to probe its essential function. In Salmonella enterica serovar Typhimurium, an extreme slow-growth phenotype caused by mutant EF-Tu (Gln125Arg, tufA499) can be rescued by mutants of RNase E that have reduced activity. We...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 21949072
DOI: 10.1128/JB.05868-11
PMCID: PMC3232887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Temperature-sensitive mutants of RNase E in Salmonella enterica.PMID 21949072Read ↗

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Reducing ppGpp level rescues an extreme growth defect caused by mutant EF-Tu.Semantic proximity Read ↗

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