Article
Cross resistance to brevetoxin-3 by kdr and super-kdr mutations in house flies.
Pesticide biochemistry and physiology - 1 May 2024
Swale Daniel R, Bloomquist Jeffrey R, McComic Sarah E, Burgess Edwin R
Abstract excerpt
The dinoflagellate Karenia brevis is a causative agent of red tides in the Gulf of Mexico and generates a potent family of structurally related brevetoxins that act via the voltage-sensitive Na+ channel. This project was undertaken to better understand the neurotoxicology and kdr cross-resistance to brevetoxins in house flies by comparing the susceptible aabys strain to ALkdr (kdr) and JPskdr (super-kdr). When...
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