Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An emerging role for epigenetic regulation of Pgc-1α expression in environmentally stimulated brown adipose thermogenesis

1 May 2017

Abstract excerpt

Metabolic disease is a leading cause of death worldwide, and obesity, a central risk factor, is reaching epidemic proportions. Energy expenditure and brown adipose tissue (BAT) thermogenesis are implicated in metabolic disease, and it is becoming evident that impaired BAT activity is regulated by gene/environment interactions. Peroxisome proliferator-activated receptor γ coactivator 1α (Pgc-1α) is a critical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Cancer, Hypoxia, and Metabolism
Share to Lipid metabolism and biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29492311
DOI: 10.1093/eep/dvx009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An emerging role for epigenetic regulation of Pgc-1α expression in environmentally stimulated brown adipose thermogenesisPMID 29492311Read ↗

Molecular and cellular regulation of thermogenic fatSemantic proximity Read ↗

Regulation of Thermogenic Adipocyte Differentiation and Adaptive Thermogenesis Through Histone AcetylationSemantic proximity Read ↗

NT-PGC-1α deficiency decreases mitochondrial FA oxidation in brown adipose tissue and alters substrate utilization in vivo.Semantic proximity Read ↗

Epigenetic dynamics of the thermogenic gene program of adipocytesSemantic proximity Read ↗

An Overview of Epigenetics in Obesity: The Role of Lifestyle and Therapeutic Interventions.Semantic proximity Read ↗

PGC-1 coactivators in the control of energy metabolismSemantic proximity Read ↗

Epigenetic Regulation of the Thermogenic Adipose ProgramSemantic proximity Read ↗

Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseasesSemantic proximity Read ↗

Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibilitySemantic proximity Read ↗

Role of physical exercise in the regulation of epigenetic mechanisms in inflammation, cancer, neurodegenerative diseases, and aging processSemantic proximity Read ↗

Blossoming 20: The Energetic Regulator's Birthday Unveils its Versatility in Cardiac DiseasesSemantic proximity Read ↗

AQP1- A regulatory factor associated with brown adipose tissue-silencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.