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Article

New alterations at potentially regulated regions of the Glial Derived Neurotrophic Factor gene in bipolar disorder.

Journal of affective disorders - 1 Jan 2014

Safari Roghaiyeh, Tunca Zeliha, Ozerdem Aysegul, Ceylan Deniz, Yazicioglu Cigdem Eresen, Sakizli Meral

Abstract excerpt

INTRODUCTION: Glial Derived Neurotrophic Factor (GDNF) plays an important role in the survival and differentiation of neurons. We examined 5'upstream and 3' untranslated region of the GDNF gene by PCR amplification and direct sequencing to explore the effect of alteration in the potentially regulated part of GDNF in bipolar disorder. MATERIALS AND METHODS: Sixty-six patients with bipolar disorder, 27 first degree...

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Source

Identifiers

PMID: 24997227
DOI: 10.1016/j.jad.2014.06.002

Genes

GDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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