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Article

Polymorphism in the 3'-UTR of LIF but Not in the ATF6B Gene Associates with Schizophrenia Susceptibility: a Case-Control Study and In Silico Analyses.

Journal of molecular neuroscience : MN - 1 Dec 2020

Moudi Mahdiyeh, Sargazi Saman, Heidari Nia Milad, Saravani Ramin, Shirvaliloo Milad, Shakiba Mansoor

Abstract excerpt

Schizophrenia (SCZ) is a multifactorial disorder caused by environmental and genetic factors. Studies have shown that various single-nucleotide polymorphisms (SNPs) in the binding sites of microRNAs contribute to the risk of developing SCZ. We aimed to investigate whether the variants located in the 3'-UTR region of LIF (rs929271T>G) and ATF6B (rs8283G>A) were associated with increased susceptibility to SCZ in a...

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PMID: 32504404
DOI: 10.1007/s12031-020-01616-6

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