Article
The skinny on brain-derived neurotrophic factor: evidence from animal models to GWAS.
Journal of molecular medicine (Berlin, Germany) - 1 Nov 2013
Waterhouse Emily G, Xu Baoji
Abstract excerpt
Obesity and its sequelae constitute a major international healthcare problem. The obesity epidemic is due in part to higher calorie diets and reduced exercise over the past 30 years; however, increasing evidence has established genetic regulation of body weight as a major contributor to obesity. Brain-derived neurotrophic factor (BDNF) regulates development and plasticity of the central nervous system, and recent...
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