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Article

Artemisinin and multidrug-resistant Plasmodium falciparum - a threat for malaria control and elimination.

Current opinion in infectious diseases - 1 Oct 2021

Dhorda Mehul, Amaratunga Chanaki, Dondorp Arjen M

Abstract excerpt

PURPOSE OF REVIEW: Artemisinin-based combination therapies (ACTs) are globally the first-line treatment for uncomplicated falciparum malaria and new compounds will not be available within the next few years. Artemisinin-resistant Plasmodium falciparum emerged over a decade ago in the Greater Mekong Subregion (GMS) and, compounded by ACT partner drug resistance, has caused significant ACT treatment failure. This...

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Identifiers

PMID: 34267045
DOI: 10.1097/QCO.0000000000000766
PMCID: PMC8452334

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