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Article

Artemisinin and partner drug resistance markers in Plasmodium falciparum from Tanzanian paediatric malaria patients, 2016–2022

1 Jul 2025

Abstract excerpt

BACKGROUND: Plasmodium falciparum malaria remains a significant public health concern in Tanzania, particularly among children under 5 years of age. The emergence and spread of partial artemisinin resistance in East Africa add to this concern. Specific mutations in the P. falciparum kelch-13 (Pfk13) and multidrug drug resistance 1 (Pfmdr1) genes are associated with artemisinin resistance and lumefantrine...

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PMID: 40598187
DOI: 10.1186/s12936-025-05447-x

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