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Article

Not Only RET but NF1 and Chromosomal Instability Are Seen in Young Patients with Sporadic Medullary Thyroid Carcinoma

29 Mar 2024

Abstract excerpt

Abstract Context Genetic analysis of sporadic medullary thyroid carcinoma (MTC) has revealed somatic variants in RET, RAS, and occasionally other genes. However, around 20% of patients with sporadic MTC lack a known genetic driver. Objective To uncover potential new somatic or germline drivers, we analyze a distinct cohort of patients with sporadic, very early–onset, and aggressive MTC. Methods Germline and...

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Hedgehog Signaling Pathway Studies
Neuroendocrine Tumor Research Advances
Thyroid Cancer Diagnosis and Treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38655100
DOI: 10.1210/jendso/bvae059

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Not Only RET but NF1 and Chromosomal Instability Are Seen in Young Patients with Sporadic Medullary Thyroid CarcinomaPMID 38655100Read ↗

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