Article
Association between STAT4 gene polymorphism and susceptibility to pulmonary tuberculosis in the Moldavian population.
International journal of immunogenetics - 1 Aug 2024
Varzari Alexander, Tudor Elena, Corloteanu Andrei, Axentii Ecaterina, Vladei Iurie, Deyneko Igor V
Abstract excerpt
Signal transducer and activator of transcription 4 (STAT4) plays a crucial role in the host immune response against Mycobacterium tuberculosis. This study investigates the association between STAT4 gene polymorphisms and pulmonary tuberculosis (TB) risk in the Moldavian population. A total of 272 TB patients and 251 community-matched controls underwent screening for functional single-nucleotide polymorphisms...
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