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Shared genetic aetiology of Alzheimer’s disease and age-related macular degeneration by APOC1 and APOE genes

1 Apr 2024

Abstract excerpt

Background: Alzheimer's disease (AD) and age-related macular degeneration (AMD) share similar pathological features, suggesting common genetic aetiologies between the two. Investigating gene associations between AD and AMD may provide useful insights into the underlying pathogenesis and inform integrated prevention and treatment for both diseases. Methods: A stratified quantile-quantile (QQ) plot was constructed...

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PMID: 38646507
DOI: 10.1136/bmjno-2023-000570

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