Article
Establishing national reference materials for genetic testing of cytochrome P450.
Pharmacogenetics and genomics - 1 Aug 2024
Jia Zheng, Huang Junju, Yang Ying, Yang Yong, Lin Wei, Qu Shoufang, Sun Nan, Zhang Wenxin, Han Lulu, Huang Jie
Abstract excerpt
OBJECTIVES: Reference materials for in-vitro diagnostic reagents play a critical role in determining the quality of reagents and ensuring the accuracy of clinical test results. This study aimed to establish a national reference material (NRM) for detecting cytochrome P450 (CYP) genes related to drug metabolism by screening databases on the Chinese population to identify CYP gene polymorphism characteristics....
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