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Article

Transmembrane determinants of voltage-gating differences between BK (Slo1) and Slo3 channels.

Biophysical journal - 16 Jul 2024

Li Qin, Chen Guanxing, Yan Jiusheng

Abstract excerpt

Voltage-gated potassium channels are critical in modulating cellular excitability, with Slo (slowpoke) channels forming a unique family characterized by their large conductance and dual regulation by electrical signals and intracellular messengers. Despite their structural and evolutionary similarities, Slo1 and Slo3 channels exhibit significant differences in their voltage-gating properties. This study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38637987
DOI: 10.1016/j.bpj.2024.04.016
PMCID: PMC11309983

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