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Novel plasma and brain proteins that are implicated in multiple sclerosis

8 Nov 2022

Abstract excerpt

Understanding how variations in the plasma and brain proteome contribute to multiple sclerosis susceptibility can provide important insights to guide drug repurposing and therapeutic development for the disease. However, the role of genetically predicted protein abundance in multiple sclerosis remains largely unknown. Integrating plasma proteomics (n = 3301) and brain proteomics (n = 376 discovery; n = 152...

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PMID: 36346149
DOI: 10.1093/brain/awac420

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