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Clinical Risks for Chronic Lymphocytic Leukemia

1 Apr 2024

Abstract excerpt

Our understanding of risk factors for the development of chronic lymphocytic leukemia (CLL) is still incomplete and includes genetic and environmental factors. CLL is one of the most familial of all cancers, yet common high-penetrance risk alleles have not been identified. Genome-wide association studies have identified many common variants with low relative risks, whereas exome-wide rare variant analysis has...

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PMID: 38626793
DOI: 10.6004/jnccn.2024.7020

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