Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA2 Polymorphisms and Breast Cancer Susceptibility: a Multi-Tools Bioinformatics Approach.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 24 Mar 2024

Jan Haris, Khan Najeeb Ullah, Al-Qaaneh Ayman M, Tasleem Munazzah, Almutairi Mikhlid H, Ali Ijaz

Abstract excerpt

BACKGROUND/AIMS: The main focus of this investigation is to identify deleterious single nucleotide polymorphisms (SNPs) located in the BRCA2 gene through in silico approach, thereby,providing an understanding of potential consequences regarding the susceptibility to breast cancer. METHODS: The GenomAD database was used to identify SNPs. To determine the potential adverse consequences, our study employed various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to Genes, BRCA2

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 38623065
DOI: 10.33594/000000689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA2 Polymorphisms and Breast Cancer Susceptibility: a Multi-Tools Bioinformatics Approach.PMID 38623065Read ↗

Computational and structural investigation of deleterious functional SNPs in breast cancer BRCA2 gene.Semantic proximity Read ↗

Molecular characterization, homology modeling and docking studies of the R2787H missense variation in BRCA2 gene: Association with breast cancer.Semantic proximity Read ↗

In silico analysis of BRCA1 and BRCA2 missense variants and the relevance in molecular genetic testing.Semantic proximity Read ↗

In silico analysis of the wild-type and mutant-type of BRCA2 gene.Semantic proximity Read ↗

BRCA1/2 germline missense mutations: a systematic review.Semantic proximity Read ↗

Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer.Semantic proximity Read ↗

In-Silico Analyses of Nonsynonymous Variants in the BRCA1 Gene.Semantic proximity Read ↗

In silico and structure-based assessment to classify VUS identified in the α-helical domain of BRCA2.Semantic proximity Read ↗

Identification and Computational Analysis of BRCA2 Variants in Mexican Women from Jalisco, Mexico, with Breast and Ovarian Cancer.Semantic proximity Read ↗

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.Semantic proximity Read ↗

Clinical and molecular characterization of the BRCA2 p.Asn3124Ile variant reveals substantial evidence for pathogenic significance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.