Article
Interindividual differences of dietary fat-inducible Mest in white adipose tissue of C57BL/6J mice are not heritable.
Obesity (Silver Spring, Md.) - 1 Jun 2024
Anunciado-Koza Rea Victoria P, Yin Haifeng, Bilodeau Crystal L, Cooke Diana, Ables Gene P, Ryzhov Sergey, Koza Robert A
Abstract excerpt
OBJECTIVE: Differences in white adipose tissue (WAT) expression of mesoderm-specific transcript (Mest) in C57BL6/J mice fed a high-fat diet (HFD) are concomitant with and predictive for the development of obesity. However, the basis for differences in WAT Mest among mice is unknown. This study investigated whether HFD-inducible WAT Mest, as well as susceptibility to obesity, is transmissible from parents to...
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