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Article

Sex-specific effects of exercise ancestry on metabolic, morphological and gene expression phenotypes in multiple generations of mouse offspring.

Experimental physiology - 1 Oct 2013

Guth Lisa M, Ludlow Andrew T, Witkowski Sarah, Marshall Mallory R, Lima Laila C J, Venezia Andrew C, Xiao Tao, Ting Lee Mei-Ling, Spangenburg Espen E, Roth Stephen M

Abstract excerpt

Early life and preconception environmental stimuli can affect adult health-related phenotypes. Exercise training is an environmental stimulus affecting many systems throughout the body and appears to alter offspring phenotypes. The aim of this study was to examine the influence of parental exercise training, or 'exercise ancestry', on morphological and metabolic phenotypes in two generations of mouse offspring....

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Identifiers

PMID: 23771910
DOI: 10.1113/expphysiol.2012.070300
PMCID: PMC3783594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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