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Cellular senescence and metabolic reprogramming model based on bulk/single-cell RNA sequencing reveals PTGER4 as a therapeutic target for ccRCC

11 Apr 2024

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is the prevailing histological subtype of renal cell carcinoma and has unique metabolic reprogramming during its occurrence and development. Cell senescence is one of the newly identified tumor characteristics. However, there is a dearth of methodical and all-encompassing investigations regarding the correlation between the broad-ranging alterations in metabolic processes...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38605343
DOI: 10.1186/s12885-024-12234-5

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