Article
Daratumumab treatment in six highly sensitised solid organ transplant recipients: A case series and literature review.
HLA - 1 Apr 2024
Lemal Richard, Blandin Lucie, Uro-Coste Charlotte, Philipponnet Carole, Geoffroy Etienne, Heng Anne-Elisabeth, Garrouste Cyril, Rouzaire Paul
Abstract excerpt
We report data on six kidney or heart recipients who were administered daratumumab to treat or prevent antibody-mediated rejection (ABMR). To date, data are scarce concerning the use of daratumumab in solid organ transplantation and most reports show a decrease in donor-specific antigen (DSA) levels and an improvement in ABMR using a multiple myeloma daratumumab administration scheme, that is, with sequential...
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