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Development and validation of a deep learning-based microsatellite instability predictor from prostate cancer whole-slide images

9 Apr 2024

Abstract excerpt

Microsatellite instability-high (MSI-H) is a tumor-agnostic biomarker for immune checkpoint inhibitor therapy. However, MSI status is not routinely tested in prostate cancer, in part due to low prevalence and assay cost. As such, prediction of MSI status from hematoxylin and eosin (H&E) stained whole-slide images (WSIs) could identify prostate cancer patients most likely to benefit from confirmatory testing to...

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PMID: 38594360
DOI: 10.1038/s41698-024-00560-7

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