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Development and interpretation of a pathomics-based model for the prediction of microsatellite instability in Colorectal Cancer

1 Jan 2020

Abstract excerpt

Microsatellite instability (MSI) has been approved as a pan-cancer biomarker for immune checkpoint blockade (ICB) therapy. However, current MSI identification methods are not available for all patients. We proposed an ensemble multiple instance deep learning model to predict microsatellite status based on histopathology images, and interpreted the pathomics-based model with multi-omics correlation. Methods: Two...

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Share to Cancer Genomics and Diagnostics
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33042271
DOI: 10.7150/thno.49864

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