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Why put yourself on a pedestal? The pathogenic role of the A/E pedestal

9 Apr 2024

Abstract excerpt

ABSTRACT Certain Escherichia coli ( E. coli ) strains are attaching and effacing (A/E) lesion pathogens that primarily infect intestinal epithelial cells. They cause actin restructuring and polymerization within the host cell to create an actin-rich protrusion below the site of adherence, termed the pedestal. Although there is clarity on the pathways initiating pedestal formation, the underlying purpose(s) of the...

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PMID: 38591884
DOI: 10.1128/iai.00489-23

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Why put yourself on a pedestal? The pathogenic role of the A/E pedestalPMID 38591884Read ↗

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