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Pushing boundaries: mechanisms enabling bacterial pathogens to spread between cells

25 Apr 2024

Abstract excerpt

ABSTRACT For multiple intracellular bacterial pathogens, the ability to spread directly into adjacent epithelial cells is an essential step for disease in humans. For pathogens such as Shigella , Listeria , Rickettsia , and Burkholderia , this intercellular movement frequently requires the pathogens to manipulate the host actin cytoskeleton and deform the plasma membrane into structures known as protrusions,...

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PMID: 38661369
DOI: 10.1128/iai.00524-23

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