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Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

1 Apr 2024

Abstract excerpt

. Here we profiled 368 plasma proteins in 657 participants ≥3 months following hospitalization. Of these, 426 had at least one long COVID symptom and 233 had fully recovered. Elevated markers of myeloid inflammation and complement activation were associated with long COVID. IL-1R2, MATN2 and COLEC12 were associated with cardiorespiratory symptoms, fatigue and anxiety/depression; MATN2, CSF3 and C1QA were elevated...

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PMID: 38589621
DOI: 10.1038/s41590-024-01778-0

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