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Severe fatigue as symptom of long COVID is characterized by increased expression of inflammatory genes in monocytes, increased serum pro-inflammatory cytokines, and increased CD8+ T-lymphocytes: A putative dysregulation of the immune-brain axis, the coagulation process, and auto-inflammation to explain the diversity of long COVID symptoms

2022-09-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> A significant proportion of patients with SARS-CoV-2 infection develops long COVID with fatigue as one of the most disabling symptoms. We performed clinical and immunologic profiling of fatigued and non-fatigued long COVID patients and age and gender matched healthy controls (HCs). <h4>Methods</h4> We included 37 long COVID patients with and 36 without severe fatigue and asses...

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Literature Corpus work
90ad82e2-d14c-57ce-9852-9ce67dfd9935
DOI
10.1101/2022.09.15.22279970
Open publication

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Severe fatigue as symptom of long COVID is characterized by increased expression of inflammatory genes in monocytes, increased serum pro-inflammatory cytokines, and increased CD8+ T-lymphocytes: A putative dysregulation of the immune-brain axis, the coagulation process, and auto-inflammation to explain the diversity of long COVID symptomsDOI 10.1101/2022.09.15.22279970
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