Article

Large scale phenotyping of long COVID inflammation reveals mechanistic subtypes of disease

2023-06-12

Abstract excerpt

One in ten SARS-CoV-2 infections result in prolonged symptoms termed ‘long COVID’, yet disease phenotypes and mechanisms are poorly understood. We studied the blood proteome of 719 adults, grouped by long COVID symptoms. Elevated markers of monocytic inflammation and complement activation were associated with increased likelihood of all symptoms. Elevated IL1R2, MATN2 and COLEC12 associated with cardiorespiratory...

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Literature Corpus work: 949b4458-2478-563d-b8fd-689d42b14bb9
DOI: 10.1101/2023.06.07.23291077

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